A most painful case of chloroform occurred at Sheffield, on Friday. Miss. NAYLOR, who resides with her brother, Mr. W. H. NAYLOR, Hanover street, auctioneer, having suffered much from tic-dolorous, kept cholorofom, which she used to allay the pain, and to induce repose.

Her friends knowing that fatal accidents had arisen from want of due care in the use of the drug, had cautioned her about it, and been desirous that she should desist from its use.

On Thursday night she was suffering from great pain, and expressed to the servant girl her intention to apply choloroform. The servant endeavoured to dissuade her, but she replied that she was not a child, and understood the quantity she could safely use. She retired to her room and nothing was heard of her during the night.

Miss. NAYLOR, not making her appearance at the usual hour next morning, the girl knocked at her door, but receiving no answer, she spoke to Mr. NAYLOR. He knocked at his sister’s door, and being unable to arouse her, forced open the door.

Miss. NAYLOR was found dead in bed with her face buried in her hands, in one of which was a handkerchief, that had been saturated with the fatal drug. An empty bottle, in which chloroform had been kept was found upon the bed, and the cork upon the dressing table.